Casper G Schalkwijk Selected Research

Thrombomodulin

3/2015	A healthy diet is associated with less endothelial dysfunction and less low-grade inflammation over a 7-year period in adults at risk of cardiovascular disease.
4/2012	Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study.
10/2011	Endothelial dysfunction and low-grade inflammation are associated with greater arterial stiffness over a 6-year period.
6/2005	Plasma levels of AGE peptides in type 1 diabetic patients are associated with serum creatinine and not with albumin excretion rate: possible role of AGE peptide-associated endothelial dysfunction.
3/2004	Increased levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine in type 1 diabetic patients with impaired renal function: correlation with markers of endothelial dysfunction.

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Casper G Schalkwijk Research Topics

Disease

72	Inflammation (Inflammations) 09/2022 - 03/2002
58	Type 2 Diabetes Mellitus (MODY) 11/2022 - 06/2003
43	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 03/2004
28	Atherosclerosis 03/2021 - 03/2002
26	Insulin Resistance 01/2022 - 03/2002
18	Obesity 04/2022 - 03/2002
17	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 09/2022 - 12/2002
12	Albuminuria 01/2022 - 01/2006
12	Hypertension (High Blood Pressure) 01/2020 - 09/2008
11	Fibrosis (Cirrhosis) 08/2015 - 09/2004
10	Hyperglycemia 11/2020 - 12/2002
9	Weight Loss (Weight Reduction) 04/2022 - 01/2017
8	Prediabetic State (Prediabetes) 01/2022 - 01/2017
8	Non-alcoholic Fatty Liver Disease 01/2022 - 07/2011
8	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 12/2006
8	Neoplasms (Cancer) 09/2021 - 06/2005
8	Heart Failure 01/2021 - 12/2007
8	Diabetic Nephropathies (Diabetic Nephropathy) 06/2013 - 05/2002
6	Myocardial Infarction 11/2021 - 05/2006
6	Overweight 01/2021 - 11/2014
6	Chronic Kidney Failure (Chronic Renal Failure) 10/2020 - 06/2005
5	Glucose Intolerance 01/2022 - 07/2007
5	Diabetes Complications 01/2019 - 05/2008
5	Diabetic Angiopathies (Diabetic Angiopathy) 04/2012 - 05/2002
4	Abdominal Obesity 01/2022 - 04/2011
4	Hyperemia 01/2022 - 01/2015
4	Colorectal Neoplasms (Colorectal Cancer) 09/2021 - 01/2020
4	Chronic Renal Insufficiency 10/2020 - 01/2019
3	Stroke (Strokes) 01/2021 - 05/2006
3	Diabetes Mellitus 11/2020 - 01/2008
3	Fructose Intolerance (Intolerance, Fructose) 06/2020 - 11/2019
3	Renal Insufficiency (Renal Failure) 05/2020 - 03/2004
3	Cerebral Small Vessel Diseases 01/2020 - 01/2020
3	Multiple Sclerosis 01/2019 - 02/2017
3	Atherosclerotic Plaque (Atheroma) 01/2019 - 05/2014
3	Hypoxia (Hypoxemia) 02/2017 - 11/2010
3	Depressive Disorder (Melancholia) 01/2017 - 01/2016
3	Rupture 10/2014 - 04/2014

Drug/Important Bio-Agent (IBA)

65	Advanced Glycation End ProductsIBA 01/2022 - 01/2002
43	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 06/2005
41	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2006
27	N(6)-carboxymethyllysine (carboxymethyllysine)IBA 11/2021 - 03/2004
22	Pyruvaldehyde (Methylglyoxal)IBA 11/2022 - 09/2006
18	C-Reactive ProteinIBA 01/2018 - 02/2003
13	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2005
13	SelectinsIBA 01/2022 - 03/2004
13	Insulin (Novolin)FDA Link 12/2021 - 03/2002
12	pentosidineIBA 10/2021 - 03/2009
11	LipidsIBA 04/2022 - 07/2007
11	von Willebrand FactorIBA 01/2022 - 03/2004
11	Serum Amyloid A Protein (Serum Amyloid A)IBA 10/2016 - 02/2011
10	CholesterolIBA 04/2022 - 05/2014
10	E-SelectinIBA 01/2022 - 03/2004
9	Retinaldehyde (Retinal)IBA 01/2022 - 12/2016
9	Triglycerides (Triacylglycerol)IBA 10/2020 - 05/2014
9	Lysine (L-Lysine)FDA Link 10/2020 - 02/2011
9	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2020 - 05/2008
9	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 08/2015 - 06/2005
8	Dietary Advanced Glycation End ProductsIBA 01/2022 - 07/2015
8	Interleukin-8 (Interleukin 8)IBA 01/2017 - 10/2011
7	Receptor for Advanced Glycation End ProductsIBA 01/2021 - 04/2008
7	HDL CholesterolIBA 01/2020 - 05/2015
7	EnzymesIBA 01/2019 - 03/2004
6	Glyoxal (Ethanedial)IBA 11/2022 - 01/2014
6	3-deoxyglucosoneIBA 11/2022 - 03/2011
6	Complement C3 (C3 Complement)IBA 01/2022 - 04/2011
6	Biological ProductsIBA 01/2022 - 11/2011
6	Complement System Proteins (Complement)IBA 03/2021 - 12/2012
6	Antihypertensive Agents (Antihypertensives)IBA 01/2020 - 04/2010
5	FructoseIBA 01/2022 - 11/2019
5	CollagenIBA 01/2020 - 01/2002
5	AlbuminsIBA 12/2016 - 05/2002
5	ThrombomodulinIBA 03/2015 - 03/2004
5	Interleukin-6 (Interleukin 6)IBA 11/2014 - 02/2011
5	AdipokinesIBA 06/2014 - 11/2010
4	Metformin (Glucophage)FDA LinkGeneric 10/2022 - 05/2008
4	Arginine (L-Arginine)FDA Link 10/2022 - 09/2006
4	Matrix Metalloproteinases (MMPs)IBA 07/2020 - 03/2015
4	LDL CholesterolIBA 01/2020 - 07/2007
4	OsteopontinIBA 01/2018 - 01/2013
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2016 - 11/2005
4	AdiponectinIBA 02/2013 - 06/2003
4	Plasminogen Activator Inhibitor 1IBA 03/2012 - 06/2005
4	Peptides (Polypeptides)IBA 01/2008 - 01/2005
3	Cell Adhesion MoleculesIBA 01/2022 - 07/2011
3	Complement Factor D (Factor D)IBA 01/2022 - 12/2018
3	Syntex adjuvant formulationIBA 01/2021 - 01/2017
3	C-PeptideIBA 10/2020 - 01/2017
3	InterleukinsIBA 01/2018 - 03/2015
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2018 - 01/2008
3	hydroxide ionIBA 01/2017 - 09/2008
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2016 - 05/2008
3	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2016 - 06/2004
3	C.I. direct red 80IBA 01/2015 - 09/2011
3	Ceruloplasmin (Ferroxidase)IBA 11/2014 - 02/2011
3	HaptoglobinsIBA 11/2014 - 02/2011

Therapy/Procedure

7	Therapeutics 01/2022 - 09/2011
3	Renal Replacement Therapy (Therapies, Renal Replacement) 10/2020 - 01/2019
3	Peritoneal Dialysis 01/2019 - 04/2004
3	Renal Dialysis (Hemodialysis) 01/2019 - 10/2013